Results 1 – 8 Download Chimico farmaceutica savelli bruno and more books of the same author and others for free. a) F. SAVELLI, O. BRUNO: Analisi chimico Farmaceutica – Editore c) G.C. PORRETTA: Analisi quantitativa di composti farmaceutici – CISU. 5 a Ed. ETS Editrice, Pisa F. Savelli, O. Bruno. Analisi Chimico Farmaceutica – Piccin, Padova, A. Carta, M. G. Mamolo, F. Novelli.

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Acid-base, and redox equilibria titrations. SID – Sistema informatico dipartimentale Direzione servizi informatici e amministrazione digitale Direzione Edilizia e Telecomunicazione. Esercitazioni individuali in laboratorio. Laurea Magistrale in Farmacia. Farmacocinetica e Farmacodinamica su Basi Chimico-Fisiche. ETS Editrice, Pisa Dipartimento di Scienze della Vita e Biotecnologie Coordinatore: The student who successfully completes the course will be able to demonstrate a solid knowledge of the main methodologies involved in an analytical process aimed at identifying the identity and the purity of unknown compounds and, in particular, of compounds included in the European Pharmacopoeia.

Scheda insegnamento — Laurea Magistrale in Farmacia

The course provides notions on the main procedures to be followed during a qualitative analysis. I processi di scoperta dei farmaci. Main metabolic phases 1 and 2 transformations.

Assessment criteria of knowledge. At the end, the student should be able to know and correctly use the basic tools present in a chemical analysis and research laboratory. Gruppi funzionali e reazioni di riconoscimento. Riconoscimento di sostanze organiche e di farmaci metallo-organici e organici inclusi nella Farmacopea Europea.


Electrical conductivity of solutions and laws of conductivity. Stoichiometric calculations, mass and volume measurements. Assessment criteria of skills.

Basic operations in organic chemistry laboratory. Strategy and tactics in drug discovery. Ricerca della struttura aromatica; ricerca dell’insaturazione attiva; acidi carbossilici; acidi solfonici; a-amminoacidi; esteri; aldeidi e.

Riconoscimento di alcune sostanze iscritte nella Farmacopea Europea. Manuale di chimica farmaceutica. Lipophilicity definitions and lipophilicity scales. Interaction of drugs with receptors full, partial or inverse agonists, antagonistsenzymes reversible, irreversible, allosteric inhibitors and other biological targets.

Direct and indirect conductimetry.

Vogel’s textbook of practical organic anaalisi – 5th Ed. Assessment criteria of behaviors. Use of analytical balance. Moreover, students will be engaged in some basic operations of organic svaelli, including purification and quality control of a reaction product.

Preparation of solutions of common reagents and standardization with volumetric methodologies. Initially the students will be trained to understand the general nature of their analytes organic, inorganic, mixed. The work in the exercitation is done either individually or in pairs, depending on its difficulty.

Identificazione sistematica di composti organici – Editoriale Grasso, Bologna, Vogel’s textbook of practical organic chemistry – 5th Ed. Wavelli organiche, inorganiche, a composizione mista; sostanze pure, impure, in miscela; comportamento delle Sostanze al calore. Individuazione dell’azoto, zolfo, alogeni, fosforo, arsenico.


Lead compound optimisation, candidate compound selection, pharmacophore.

Direct analysis of a strong and a weak acid solution with conductimeter. Selectivity toward different isozymes and receptor subtypes.

Target identification and validation, lead identification. Theorical basis of chromatographic separations, and TLC laboratory practice with samples of different compounds mixtures. Filtration and recrystallization of an organic reaction product, with TLC control.


Determinazione di alcune costanti fisiche. Laboratory class for in total 24 hours, divided into 6 sessions. Conductivity cells and conductimeter.

Prodrugs and bioprecursors strategy. Drug distribution, acid-base properties. Guida pratica al riconoscimento delle sostanze iscritte nella V edizione della Farmacopea Europea. Natura di un campione analitico.

The final target is to set a rational basis for the study of the systematic medicinal chemistry. The drug discovery process. Cerca nel sito solo nella sezione corrente.

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