CORYNEBACTERIUM STRIATUM PDF

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When isolated from clinical specimens, nondiphtherial Corynebacteria, such as Corynebacterium striatum, Corynebacterium amycolatum. ABSTRACT. We describe an unusual cluster of Corynebacterium striatum infections in 21 patients with chronic obstructive pulmonary disease (COPD) admitted. Objective: To evaluate the clinical significance of and describe factors associated with Corynebacterium striatum infection. Methods: A.

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Thus, fluoroquinolone resistance emerged in clinical isolates of C. Unwanted side reactions such as threonine and asparagine production can occur if a buildup of intermediates occurs, so scientists have developed mutant strains of C.

Corynebacterium diphtheriae Diphtheria Corynebacterium minutissimum Erythrasma Corynebacterium jeikeium Group JK corynebacterium sepsis. The term “diphtheroids” is used to represent corynebacteria that are non pathogenic ; for example, C. Retrieved 6 May Agricultural and Biological Chemistry. Some PFGE patterns were more frequently isolated, striaatum the existence of a few more prevalent clones. Corynebacterium striatum is recognized as a true pathogen when isolated stiatum several samples from sterile body sites or from indwelling medical devices 12.

National Center for Biotechnology InformationU.

Corynebacterium – Wikipedia

Multidrug-resistant Corynebacterium striatum pneumonia in a heart transplant recipient. Patient-to-patient spread of a single strain of Corynebacterium striatum causing infections in a surgical intensive care unit.

Single mutations stroatum the residue Ser or in the residue Asp described by Sierra et al.

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Erythromycin and clindamycin were inactive against corhnebacterium majority of our C. This would eventually lead this strain to become a secondary colonizer in immunocompromised hosts [ 8 ].

Corynebacteria grow slowly, even on enriched media. During the period —, 90 strains recovered from clinical specimens submitted for routine culture to the microbiology laboratory of the FHU corynebacterimu were assigned to the genus Corynebacterium on the basis of colony morphology, Gram staining, and catalase production.

In the present case, we report a catheter-related bloodstream infection caused by C.

Corynebacterium striatum Bacteremia Associated with a Catheter-Related Blood Stream Infection

Forty-six out of the 63 C. The genus Corynebacterium was created by Syriatum and Neumann in as a taxonomic group to contain the bacterial rods responsible for causing diphtheria. Nondiphtherial corynebacteria have been frequently dismissed as a contaminant when isolated from clinical materials. It can be spread within a hospital.

Case Reports in Infectious Diseases

However, in recent years, they have been reported as emerging opportunistic pathogens in immunocompromised patients with end-stage cancer, hematologic malignancy, and critical condition [ 2 ]. Pathogenic species in other animals include C. The mef A-E gene was not found in any strain tested. Methods Bacterial strains and growth conditions During the period —, 90 strains recovered from clinical specimens submitted for routine culture to the microbiology laboratory of the FHU hospital were assigned to the genus Corynebacterium on the basis of colony morphology, Gram staining, and catalase production.

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Galimand M, et al. More recently, Gomila et al. Accurate diagnosis of the infection and prompt management helped in a favourable outcome for the patient. Most of the strains resistant to fluoroquinolones showed a double mutation leading to an amino acid change in positions 87 and 91 in the quinolone resistance-determining region of the gyrA gene.

Daptomycin has also been proven to be active against C. Corynebacterium diphtheriae and nondiphtherial Corynebacteriacollectively referred to as diphtheroids. Boltin D, et al. Performance Standards for Antimicrobial Susceptibility Testing.

The bacterium was detected from the removed central venous catheter tip too. Report of a case with polymicrobial endocarditis related to multiresistant strains. MLS resistance in Corynebacterium spp. Introduction The Corynebacteria are a group of aerobic, Gram-positive, catalase-positive, nonsporulating, generally nonmotile rods [ 1 ].

Implication of ermX genes in macrolide and telithromycin resistance in Corynebacterium jeikeium and Coryneacterium amycolatum. It progressed to disseminated striatym coagulation and disturbance of consciousness on day 67 of admission.

As expected, the 10 C. Susceptibility of 63 Corynebacterium striatum clinical isolates to 16 antimicrobial agents. The ampC gene was detected in 22 of the 28 cefotaxime-resistant C.

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