FOSCARNET PRESCRIBING INFORMATION PDF

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are concise point-of-care prescribing, dosing and administering information to Prior to the initial foscarnet infusion, establish diuresis by administering Prehydrate with mL NS or D5W before first infusion to decrease risk for nephrotoxicity. See prescribing information for dose adjustments for CrCl < Group: antiviral. Solution for injection, 24 mg/ml ml, ml [non-EDL]. General information. Foscarnet is a non-nucleoside pyrophosphate analogue given.

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Major When possible, avoid concurrent use of foscarnet with other drugs known to prolong the QT interval, such as venlafaxine. Major When possible, avoid concurrent use of foscarnet prescribiing other drugs known to prolong the QT interval, such as vorinostat. Fluphenazine is associated with a possible risk for QT prolongation. Foscarnet injection is also used to treat herpes simplex virus HSV infections of the skin and mucus membranes mouth, anus in people whose immune system is not fkscarnet normally and when treatment with acyclovir did not help.

Perhexiline The risk or severity of Presribing prolongation can be increased when Foscarnet is combined with Perhexiline. Severe Concurrent use of gallium nitrate with other potentially nephrotoxic drugs, such as foscarnet, may increase the risk for developing severe renal insufficiency. Indigotindisulfonic Acid Foscarnet may decrease the excretion rate of Indigotindisulfonic Acid which could result in a higher serum level.

Aceclofenac The risk or severity of nephrotoxicity can be increased when Aceclofenac is combined with Foscarnet. Famotidine The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Famotidine. Ibuproxam The risk or severity of nephrotoxicity can be increased when Ibuproxam is combined with Foscarnet.

Adverse effects Nephrotoxicity, hypomagnesaemia, hypocalcaemia, hypokalaemia, hypophosphataemia, hypercalcaemia accompanied by perioral tingling, numbness in the extremities, paraesthesiahyperphosphataemia, headache, nausea, vomiting, rash, convulsions though to be associated with hypocalcaemiagenital ulceration, and anaemia. Felodipine The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Felodipine. Because of the potential for TdP, use of foscarnet with dronedarone is contraindicated.

Indometacin The risk or severity of nephrotoxicity can be increased when Indomethacin is combined with Foscarnet. Fomepizole Foscarnet may decrease the excretion rate of Fomepizole which could result in a higher serum level. Major When possible, avoid concurrent use of foscarnet with other drugs known to prolong the QT interval, such as tacrolimus. Sudden death and QT prolongation have been reported in patients who received nilotinib therapy.

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Lopinavir; ritonavir is also associated with QT prolongation. If QTcF is greater than msec, interrupt vandetanib dosing until the QTcF is less than msec; then, vandetanib may be resumed at a reduced dose. Cefcapene The risk or severity of nephrotoxicity can be increased when Cefcapene is combined with Foscarnet. Rilpivirine The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Rilpivirine.

Twenty-eight of the patients experienced adverse events and five patients suffered no ill effects in connection with foscarnet overdosing. Quinidine administration is also associated with QT prolongation and TdP. If the administration of Foscavir does not lead to a therapeutic response or leads to a worsened condition after an initial response, this may result from a reduced sensitivity of viruses towards foscarnet.

Foscavir (foscarnet sodium) dose, indications, adverse effects, interactions from

Enter medicine name or company Start typing to retrieve search suggestions. Animal studies have shown that foscarnet distributes into informatiom milk at concentrations that are three times greater than maternal plasma concentrations. Quinine The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Quinine. ECG although the toxicological studies performed did not disclose any such effects.

Foscavir 24 mg/ml Solution for Infusion

Your doctor may not want you to receive foscarnet injection. Dobutamine Foscarnet may decrease the excretion rate of Dobutamine which could result in a higher serum level. Bunaftine The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Bunaftine. Droxicam The risk or severity of nephrotoxicity can be increased when Droxicam is combined with Foscarnet.

Cefmenoxime The risk or severity of nephrotoxicity can be increased when Cefmenoxime is combined with Foscarnet. Major When possible, avoid concurrent use of foscarnet with other drugs known to prolong the QT interval, such as alfuzosin.

When diuretics are indicated, thiazides are prescriving. Bismuth Subsalicylate; Metronidazole; Tetracycline: Chloroquine The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Chloroquine. No dilution is necessary if administered via a central vein. Tamoxifen has also been reported to prolong the QT interval, usually in overdose or when prescribihg in high doses.

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Sunitinib The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Sunitinib. Glycerol phenylbutyrate Foscarnet may decrease the excretion rate of Glycerol phenylbutyrate which could result in a higher serum level. Moderate Avoid concurrent use of loop diuretics with foscarnet. Lamivudine; Tenofovir Disoproxil Fumarate: Phenelzine Foscarnet may decrease the excretion rate of Phenelzine which could result in a higher serum level.

Cinnamaldehyde Foscarnet may decrease the excretion rate of Cinnamaldehyde which could result in a higher serum level. Oxyquinoline Foscarnet may decrease the excretion rate of Oxyquinoline which could result in a higher serum level.

Foscarnet – DrugBank

Do not drive a car or operate machinery until you know how this medication affects you. Acrivastine Foscarnet may decrease the excretion rate perscribing Acrivastine which could result in a higher serum level. Pharmaceutical interactions incompatibilities for infusion are described in section 6.

Particular caution is recommended for patients in infoormation changes in electrolyte balance may increase the risk of developing neurologic and cardiac dysfunction, such as those individuals who are receiving other drugs that influence serum electrolytes, patients with baseline renal impairment, or those with preexisting cardiac disease, seizure disorder or other neurological disease.

Isoflavone Foscarnet may decrease the excretion rate of Isoflavone which could result in a higher serum level.

Foscarnet Injection

Instruct patients to avoid driving or operating machinery until the effects of foscarnet on the individual patient are known. Fluorescein The excretion of Fluorescein can be decreased when combined with Foscarnet.

Isosulfan blue Foscarnet may decrease the excretion rate of Isosulfan blue which could result in a higher serum level. Prolongation of the QTc interval and ventricular arrhythmias have been reported in patients treated with ivosidenib. Arsenic trioxide The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Arsenic trioxide. In some cases, patients had confounding risk factors such as underlying cardiac disease, electrolyte abnormalities, and other concomitant medications.

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