Yaws is a non-venereal tropical infectious disease caused by the organism Treponema pertenue.[1] This organism is closely related to the. Yaws is an infectious tropical disease caused by the spirochete (spiral shaped) bacterium known as Treponema pertenue. The disease presents in three stages . Yaws is a tropical disease characterized by a primary cutaneous lesion, followed by a granulomatous skin eruption, and sometimes by late destructive lesions of.

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One to 2 months after inoculation, up to 2 yearspatients develop disseminated papillomatous or ulcerative lesions with macular or hyperkeratotic palmoplantar involvement.

These spirochetes are fragile outside of their host vectors and are rapidly killed by exposure to heat, oxygen, and drying. Two countries that used to harbor disease now boast eradication and those are India and Ecuador. fframbesia

Epub Feb Global epidemiology of yaws: Yaws; Endemic Nonvenereal and Congenital Syphilis. Most often the diagnosis is made clinically. Yaws has required global coordination, as endemic areas often are under-equipped for diagnosis or treatment. This disease affects the nerves that are located outside the central nervous system peripheral nervesand the skin, mucous membranes, and eyes.

The disease is characterized by an acute phase followed by a chronic, relapsing course in a minority of patients. PMC ] [ PubMed: Yaws affects males and females in equal numbers and is most common in children between the ages of six and For many years it has been customary to consider nonvenereal syphilis and yaws as separate entities. Eradication of yaws–the Morges strategy. Benzathine penicillin subsequently supplanted this as it was found to have prolonged treponemicidal levels and convenient dosing.


Dark field microscopy of samples taken from early lesions particularly ulcerative lesions may show the responsible organism. Once positive, these latter 2 tests are positive for life. Authors Luke Maxfield 1 ; Jonathan S. Bacterium-related cutaneous conditions Syphilis Infectious diseases with eradication efforts Neglected diseases Tropical diseases.

These antibiotic drugs may also be used to prevent this disease in family members and others who are in frequent contact with affected individuals. To access free multiple choice questions on this topic, click here. These lesions change in color and eventually lose all color depigmentation. About News Events Contact. Retrieved 5 August One, known as goundou syndrome, is characterized by inflammation and swelling of the tissues surrounding the nose paranasal swellingas well as overgrowth of the bones in the same region of the face hypertrophic osteitis.

Now the experts, differing among themselves, have raised doubts about the validity of this “separate disease” concept. Azithromycin is an antibiotic used for infections of the respiratory tract, very common in our pharmacies. Capuano C, Ozaki M.

Rare Disease Database

Yaws is spread by direct contact with the fluid from a lesion of an infected person. Additionally, as the treponemes are indistinguishable serologically and early clinical features may overlap accurate diagnosis may be difficult.

Nearby “daughter yaws” may also appear simultaneously. Chlamydophila Chlamydophila psittaci Psittacosis Chlamydophila pneumoniae.

History and Physical The disease is characterized by primary, secondary, and tertiary stages. Radius, ulna, and phalanges are the most frequent. Treatment is normally by a single intramuscular injection of penicillinor by a course of penicillin, erythromycin or tetracycline fgambesia. Radiologic abnormalities reveal dactylitis and osteoperiostitis. By the number of cases was Government funding, and some supported by private industry, are posted on this frrambesia web site.


Eradication of infectious diseases. However, there has been a resurgence of yaws in certain countries in Africa and Southeast Asia. From Wikipedia, the free encyclopedia. Mass treatment campaigns in the s reduced the worldwide prevalence from 50— million to fewer than 2. This page was last edited on 4 Decemberat tropkcal The symptoms may remain dormant for years.

Tropical Medicine Central Resource

Each year it affects more thanchildren between the ages of 5 and 15 in 13 endemic countries of West Africa, Southeast Asia and the Pacific.

A framgesia of epidemiology, clinical signs and symptoms, direct visualization, and serologic data are required to establish the diagnosis.

Infectious diseases Bacterial diseases: Yaws is most commonly seen among children in tropical regions and is spread by skin-to-skin contact. Diagnosis The diagnosis of stage 1 and stage 2 yaws is made by microscopic examination of tissue samples darkfield examination from the skin lesions of affected individuals.

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